A key advantage of this assay is its modular design, allowing researchers to choose between direct sequencing of enriched fragments for efficient genome-wide mapping or adding an enzymatic conversion ...

A few years ago, the advent of technology known as CRISPR was a major breakthrough in the scientific world. Developed from a ...

DNA sequencing is any chemical, enzymatic or technological procedure for determining the linear order of nucleotide bases in DNA. Sanger sequencing by replicative synthesis in the presence of ...

Restriction enzymes will cut up, or cleave, DNA molecules wherever they encounter a specific sequence of bases. For example, one type of enzyme will cleave DNA wherever it encounters the sequence ...

New England Biolabs (NEB ®) today announced the launch of NEBNext ® Enzymatic Methyl-seq (EM-seq ™), an enzyme-based alternative to bisulfite sequencing for methylation analysis. Bisulfite treatment ...

He predicted that the restriction enzyme and the modification enzyme act on the same DNA sequence, called a recognition sequence. In this way, the bacterial cell's own self-defense mechanism ...

Among the major classes of RNAs in the cell, tRNAs remain the most difficult to characterize via deep sequencing approaches, as tRNA structure and nucleotide modifications can each interfere with cDNA ...