The neurons exhibited reduced mitochondrial respiration and impaired energy production, correlating with the extensive S-nitrosylation of critical enzymes. The Role of Succinate and the Krebs Cycle ...

While this research focused on αKGDH, other enzymes within the TCA cycle may also be affected, necessitating further investigation. Beyond their immediate findings, the researchers’ use of ...

Enzymes lower the activation energy necessary ... Learn more about the energy-generating processes of glycolysis, the citric acid cycle, and oxidative phosphorylation. Protein surfaces are ...

Mitochondrial genome contributes polypeptide subunits to the five enzyme complexes that comprise ... of carbohydrates (the tricarboxylic acid (TCA) cycle) and fatty acids is coupled to the ...