The latest research published in Genes & Diseases unveils groundbreaking insights into the role of the aging process and the ...

Epithelial–mesenchymal transition (EMT) is an important process during development by which epithelial cells acquire mesenchymal, fibroblast-like properties and show reduced intercellular ...

While cancer-associated fibroblasts (CAFs) significantly influence tumor progression, their temporal dynamics remain poorly understood. We investigated time-dependent interactions between non-small ...

Since the 1950s, researchers have used a famous method invented by Wallace Coulter known as "flow cytometry" to characterize ...

Researchers found that clinically achievable doses of curcumin, the active compound in turmeric, target and suppress ...

Chronic kidney disease (CKD) is typically associated with severe fibrosis, the exact pathogenesis of which remains unclear.

Background: Tumor cells that have undergone an epithelial-to-mesenchymal (EMT)-like phenotypic transformation in situ have been implicated in tumor cell invasiveness and disease progression.

The study uncovers how ovarian ECM tropism influences endometriotic cell adhesion, paving the way for novel strategies to ...

MetasTx, LLC, a biotechnology company focused on preventing the metastasis of solid tumor cancers – like prostate, breast and skin, announced today it has received a Small Business Innovation Research ...

Background: Epithelial-mesenchymal transition (EMT) has been associated with EGFR inhibitor resistance in preclinical studies of head and neck squamous cell carcinoma (HNSCC). Recently, we developed ...

Glioblastoma (GBM) is the most common malignant primary brain tumor in adults. GBM displays excessive and unfunctional vascularization which may, among others, be a reason for its devastating ...