Erythema migrans and erythema multiforme both cause target- or bull’s-eye-shaped lesions. Erythema migrans is due to Lyme disease. Erythema multiforme is an immune-mediated hypersensitivity skin ...

They may look like hives or somewhat round bull’s-eye targets. The center of the lesions is typically darker with lighter edges. In erythema multiforme minor, lesions are often circular and less ...