The modulation of pain involves changing or inhibiting transmission ... Some types of neuropathic pain may develop when the PNS has become damaged, causing the pain fibres to transmit pain impulses ...

Sensory nerve fibres with a myelin sheath ... the periaqueductal grey (the primary control centre for descending pain modulation) to the brainstem and then act on spinal signalling.

During modulation, the last stage of pain transmission ... and only one of them can win. If many A beta fibres are activated, pain signalling is reduced; this is the principle of the gate control ...

Researchers investigate this system with a research method called 'Conditioned Pain Modulation,' or CPM for short. "This records how strongly a painful stimulus inhibits the experience of another ...

The key seems to be a more effective pain-modulation system, a discovery that can benefit people seeking help for their self-harm. Researchers at Karolinska Institutet in Sweden might have found ...

A publication from Acta Pharmaceutica Sinica B discusses allosteric modulation of G protein-coupled receptors as a novel therapeutic strategy in neuropathic pain. Neuropathic pain is a debilitating ...

conditioned pain modulation, and exercise-induced hypoalgesia. Individuals who had experienced symptomatic COVID-19 were found to have impaired conditioned pain modulation. Individuals with ...

The reaction, known as conditioned pain modulation (CPM) or “pain inhibits pain,” is used to assess patients’ physiological response to pain. People’s bodies to varying degrees inherently ...

Share on Pinterest A recent study used computational methods to identify novel compounds that activate receptors involved in pain modulation without sedation. Peter Dazeley/Getty Images Research ...

Researchers investigate this system with the research method called Conditioned Pain Modulation, or CPM for short. "This records how strongly a painful stimulus inhibits the experience of another ...