Although it can be the result of conditions such as syphilis, tumors, and gigantism, the most common disease that causes a non-cancerous overgrowth of the maxilla is craniofacial fibrous dysplasia ...

Craniofacial fibrous dysplasia is a histologically benign disease 13, 14; however, our series at a tertiary referral centre demonstrates that its presentation usually occurs early in life and a ...

Emanuel Zayas, 14, was diagnosed with a rare disorder called polyostotic fibrous dysplasia. ... in which doctors will use bone from his hip to reconstruct part of his cheekbone, upper jaw, and nose.

Fibrous dysplasia of the bone can be diagnosed with routine imaging tests like X-ray or MRI.Most cases are diagnosed in adolescence and young adulthood and remain unchanged throughout life.

Fibrous dysplasia and the McCune–Albright syndrome constitute a rare mosaic disorder caused by somatic activating mutations of Gα s (the G-protein subunit α s).Characteristic manifestations ...

Fibrous dysplasia is a rare, mosaic disorder that leads to fractures, pain, and disability. Gain-of-function GNAS variants alter skeletal stem-cell differentiation, which results in the formation ...

"This trial is the culmination of 25 years of clinical research at NIDCR to understand the underlying mechanisms of fibrous dysplasia and to identify promising treatments," said NIDCR Director ...

Fibrous dysplasia is a congenital condition that affects bone growth and development. Instead of maturing into solid bone, affected bones stay at the immature fibrous stage so are weak and misshapen.