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Historically, DNA sequencing has relied on the exact same process of copying DNA—in fact, ... For starters, people got rid of the radioactivity by replacing it with a fluorescent tag.
Credit: Kateryna Kon/Science Photo Library/ What is DNA, and how does it work? You don't need a degree in genetics to understand. Here, we'll give an overview of DNA and answer questions ...
Next-generation sequencing (NGS) has made analyzing DNA faster and cheaper, with effects felt in the lab, clinic, and beyond. A set of newly-launched technologies are offering a twist on the ...
In Helicos Biosciences’ method, individual DNA strands extracted from cells are sequenced by iterative cycles of base addition. Credit: Helicos Biosciences The first human genome sequence cost ...
1 machine, 4 weeks now enough to sequence human genome Researchers have used a new machine that sequences millions of small DNA … John Timmer – Aug 10, 2009 2:15 pm | 24 ...
It was not so long ago that sequencing even tiny snippets of DNA was a costly, cumbersome process that required access to a state-the-art lab. Today, we ...
In 1986, a company named Applied Biosystems began to manufacture automated DNA sequencing machines based on the Sanger method (Figure 1). These machines used fluorescent dyes to tag each ...
Antibiotics are one of the greatest triumphs in the history of medical science—but these lifesaving tools have a dark side.
Teams led by LMU chemist Philip Tinnefeld have now published two studies showing how DNA origami and fluorescent probes can be used to release molecular cargo in a targeted manner.
The human genome is made of more than 6 billion letters, and each person has a unique configuration of As, Cs, Gs, and Ts—the molecular building blocks that make up DNA. Determining the sequence ...
Since 1950, a method called Edman degradation has been used to sequence proteins by chemically chopping off and identifying one amino acid at a time. But that process uses strong acid, which can ...