PPIs bind to and block an enzyme in the gastric parietal cells known as the proton pump, effectively reducing the production of gastric acid. PPIs are prodrugs, which means that they are taken as ...

In the stomach, parietal cells are responsible for acid production. They react not only to the body's own messenger molecules, but also to bitter-tasting food constituents such as caffeine.

A study suggests that “chief” cells in the stomach act as reserve stem cells that are activated by tissue damage and may be the long-sought source of gastric cancer. “This is the first definitive ...

Many experts maintain that GERD is caused by dysfunction of the gastroesophageal barrier and that gastric acid secretion ... measure of enterochromaffin cell mass, were significantly higher ...