Imprinting is yet another process involved in eukaryotic gene regulation; this process involves the silencing of one of the two alleles of a gene for a cell's entire life span. Imprinting affects ...

Gene regulation in our cells—the decision on which proteins are produced for the various processes of the cell—is strictly ...

Small nucleolar RNAs (snoRNAs) are non-coding RNA molecules whose role in gene regulation and association with certain ...

The turning on of this single gene results in an apparent freak of nature. Mice whose agouti gene is "on" are also more likely to suffer from diabetes and cancer as adults. The implications of ...

In vertebrates, the skeleton of different regions of the body arises from different precursor cells. Researchers have now discovered that these skeletal cells do not just differ in their developmental ...

Small nucleolar RNAs (snoRNAs) are non-coding RNA molecules whose role in gene regulation and their association with certain diseases, such as inflammatory bowel disease (IBD) or colorectal cancer, ...

Metabolic and regulatory networks may be expanded by coupling high-throughput phenotyping and gene expression data with the predictions of a computational model. (Reprinted with permission, Nature, ...

“It was probably in about 2015 that we started working on the idea of more of a designer gene repression loop,” said Nicole Becker, a molecular biologist at the Mayo Clinic and study coauthor. In the ...

Transcriptional regulation is important. An array of gene promoters in the human papillomavirus (HPV) early region may be actively engaged in transcription of the genome and controlled in response ...

More information: Hye-In Son et al, Population-level amplification of gene regulation by programmable gene transfer, Nature Chemical Biology (2025). DOI: 10.1038/s41589-024-01817-9 ...

The course explores gene regulation in eukaryotes from nuclear organisation to cytosolic control, with a focus on animals and humans. The molecular mechanisms of transcription within a chromatin ...

Along our journey, we shall reveal basic principles of gene regulation. We aim to exploit the new knowledge to help devise novel treatments of many diseases that stem from misregulated gene ...