RNA gene scissors (CRISPR-Cas13) are gaining significant attention as a next-generation gene therapy with fewer side effects.

A team led by Professor Won Do Heo from the Department of Biological Sciences, KAIST, has developed a pioneering technology ...

Peptides are among the most intriguing biomolecules investigated in scientific research. Despite their relatively simple ...

Conventional transcriptomic techniques have revealed much about gene expression at the population and single-cell level—but ...

Li believes cells sometimes purposely select transcripts doomed for NMD ... that increase unproductive splicing often decreased gene expression levels," Li said. "This shows that there this ...

Sizeable differences in gene expression means and ratios—based solely upon where genes are located on a plasmid (gene syntax)—have been discovered by researchers at Dartmouth College.

These proteins directly modulate gene expression programs in the brain ... in monoamine concentrations can lead to their selective utilization by TG2, which could then trigger new histone ...

CHAF1B, a histone chaperone component of the chromatin assembly factor-1 complex, is overexpressed in multiple cancers and ...

and consequently do not provide particularly tight control of the transgene's expression. Rgenta has developed a platform for imparting gene therapy vectors with selective, dose-dependent ...

Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence. 1 The name epigenetics comes from the Greek prefix “epi”, which means on top ...

But a study published November 9 in ACS Central Science finds that microRNAs (miRNAs) can also amplify gene expression. “It changes the landscape of microRNA,” Lara Mahal, a chemist at the University ...