If sugar is always your jam, your DNA may be to blame. An international team of researchers says that a genetic variation in ...

Perhaps the most important potential problem in conditional gene-targeting experiments using Cre recombinase is that of Cre toxicity. Although most cre-transgenic mouse strains seem to develop ...

After the targeting vector is made, it is used to knock out one copy of the target gene in mouse embryonic stem (ES) cells (Figure 2). But why must mouse ES cells be used? Why can't the targeting ...

The team of experts began by investigating dietary behaviour in mice lacking the SI gene. They found that the animals ...

Investigator submits a targeting strategy and demonstrates a proven screening protocol. After approval of investigator’s approach the core will initiate electroporation in mouse ES cells. Investigator ...

Editas Medicine announced proof-of-concept data for a gene-editing approach for sickle cell disease that doesn't need a stem ...

says the fluorescent green jelly fish gene given to the mice in their study becomes integrated into the entire mouse genome. The scientists can then see whether targeting the genome with CRISPR ...

$2,100 $1,995 $3,780 Generation of transgenic mice by DNA microinjection (BAC) $2,415 $2,300 $4,350 Gene targeting in mouse ES cells and chimera production – 129 ES cells $9,555 $9.085 $17,200 Gene ...

The gene therapy, called P-KLKB1-101, edited KLKB1 to therapeutic levels in mice with just a single dose ... that its in vivo CRISPR gene therapy targeting the same gene reduced monthly attacks ...

We also suggest one arm being no larger than 1 kb to allow for PCR verification of proper targeting. For labs that do not routinely clone, we suggest using gene synthesis services ... Friday - 0.1 ml ...

Researchers find that a gene linked to Alzheimer's triggers inflammation in healthy brain immune cells, offering new insights ...

BEIJING, Nov. 12, 2024 /PRNewswire/ -- Tsingke has delivered high-quality biotechnology services and products to nearly 300,000 users globally. The number of high-level academic papers published using ...