However, when the researchers blocked an earlier step in glycolysis, the enzyme glucose-6-phosphate isomerase, this had no effect on the growth of the cancer cells. "The glycolytic enzyme aldolase ...

glucose-6-phosphate dehydrogenase (G6PD), which is a rate-limiting enzyme in the pentose-phosphate pathway (PPP), an essential process in glycolysis. First, they validated the screening results by ...