This research indicates that Doxorubicin (Dox)-resistant TNBC cells exhibit increased glycolysis and ATP generation compared ...

Glycolysis is the breakdown of glucose to extract energy for cellular metabolism. "We demonstrated in the study that there's a link between cellular metabolism and the immune system.

Scientists affiliated with the Center for Research on Inflammatory Diseases (CRID), hosted by the University of São Paulo (USP) in Brazil, have discovered that an enzyme involved in key metabolic ...

The pyruvate dehydrogenase complex (PDHc) plays a key role in metabolism by linking glycolysis to the tricarboxylic acid cycle and converting pyruvate into acetyl-CoA. However, due to its large ...

During photosynthesis, an enzyme called rubisco catalyzes a key reaction—the incorporation of carbon dioxide into organic ...

A groundbreaking new study has found that triple-negative breast cancer cells are missing a key enzyme that other cancer cells contain — providing insight into potential therapeutic targets to ...

Macrophages are immune cells with a split personality: some fight tumors, while others help them grow. In breast cancer, most ...

The article describes the role of PKM2 (pyruvate kinase M2), the enzyme responsible for the final step of glycolysis, in the development and maintenance of the exacerbated inflammation typical of ...

However, when the researchers blocked an earlier step in glycolysis, the enzyme glucose-6-phosphate isomerase, this had no effect on the growth of the cancer cells.

In addition to the acute regulation of key regulatory enzymes, glycolysis is regulated by a transcriptional mechanism that is activated during feeding conditions.

A groundbreaking new study led by the University of Kentucky Markey Cancer Center's Dr. Peter Zhou found that triple-negative breast cancer cells are missing a key enzyme that other cancer cells ...