Direct evidence that BRII-179-induced functional antibody responses can contribute to increased and sustained HBsAg loss rateNew insight in utiliz ...

Another promising approach is the development of curative combinations. These combinations combine different therapies, such as antiviral drugs and immune-based therapies, to achieve a cure for HBV.

Chronic hepatitis B virus (HBV) infection continues to pose a major global health threat. Home ... the researchers hope to uncover new pathways for a functional cure for chronic hepatitis B.

The phase 2b B-Clear study enrolled 457 patients with chronic HBV; 227 were receiving NA therapy, and 230 were not. Participants were randomly assigned to receive weekly subcutaneous injections of ...

Hepatitis B e-antigen seroconversion in childhood and low hepatitis B surface antigen titers after seroconversion independently predicted functional cure in chronic HBV-infected patients followed ...

Approximately 70% of previous nonresponders to the HBV vaccine developed a response after HCV treatment and cure. Age, HIV status and fibrosis degree did not seem to impact vaccine response.

Hepatitis B virus (HBV) remains a major public health concern despite effective vaccines. ... Roca Suarez AA, Zoulim F. Opportunities and challenges for hepatitis B cure.

Drug combination reaches key threshold for 'functional cure' of chronic liver infection that affects more than 250 million people worldwide An international team of researchers led by Chinese ...

Hepatitis C and hepatitis B viruses both attack the liver, eventually causing deadly cirrhosis or cancer. But while antivirals can cure 95 percent of HCV infections, its cousin HBV has long eluded ...

Virion Logo (PRNewsfoto/Virion Therapeutics, LLC) These Phase 1b data, on the first 27 chronically infected hepatitis B patients, on nucleos(t)ide antiviral therapy, all of whom received a single ...

As an oral drug administered once weekly, DF-006 has the potential to be the immunomodulator of choice in combination HBV cure regimens”, said Dr. Ed Gane, Professor of Medicine at the ...