MDA5 is a critical cytoplasmic RNA sensor capable of triggering type I interferon pathways. This study shows that the E3 ...
34 By modeling the protein, the ligand, and the solvent at the atomistic level, they observed that in the presence of the small molecule, disordered amyloid-β adopted less hydrophobic conformations, ...
In summary, these BLI data demonstrate that B. subtilis MinD is capable of binding membrane in both monomeric and dimeric form, while the presence of ATP in the binding pocket appears to affect both ...