Hepatic stellate cells control liver function and regeneration Date: March 12, 2025 Source: German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) ...

Biological actions of hepatic stellate cells (HSCs) during liver fibrogenesis and potential sites for therapeutic intervention. Comments 3090D553-9492-4563-8681-AD288FA52ACE ...

Stellate cells in the liver control regeneration and fibrosis Peer-Reviewed Publication. German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) ...

Hepatic stellate cell-expressed endosialin balances fibrogenesis and hepatocyte proliferation during liver damage. EMBO Molecular Medicine , 2015; DOI: 10.15252/emmm.201404246 Cite This Page : ...

A research team has identified the transcription factor Lhx2 (LIM homeobox protein 2) as a key regulator in hepatic stellate cells. Lhx2 was found to simultaneously promote liver regeneration and ...

In healthy liver, quiescent hepatic stellate cells (HSCs) participate in the homeostasis of extracellular matrix and store vitamin A. After injury, HSCs activate and participate in the wound-healing ...

More information: Takao Seki et al, Intercellular communication between hepatic stellate cells and myofibroblasts mediated by osteopontin and FGF18 promotes liver fibrosis, iScience (2025). DOI ...

Researchers from Columbia University and the German Cancer Center have found that stellate cells—star-shaped liver cells long known as the main perpetrators in liver fibrosis—have a commanding role in ...

Until now, doctors knew hepatic stellate cells mainly as drivers of liver fibrosis. The actual functions of this cell type have hardly been studied to date. Researchers from the German Cancer ...

Hepatic Stellate Cells as a Target for the Treatment of Liver Fibrosis. Ramón Bataller, MD, and David A. Brenner, MD, University of North Carolina at Chapel Hill, School of Medicine, ...