We were trying to learn how certain animals lost their regeneration capacity during evolution and then put back the ...

Finding Heterogeneous Loci with Human-Mouse Cell Hybrids. Bert Vogelstein has an unusual complaint about the humans whose genetic defects he studies: "We're ... the resulting amplicons. Yet if a chunk ...

Gene–environment interactions can be investigated using genetically heterogeneous mouse models, which allow us to identify how genetic modifiers of tumour induction and progression interact with ...

The work entitled “Gene print-based cell subtypes annotation of human disease across heterogeneous datasets with gPRINT” was published on Protein & Cell (published on Mar. 14, 2025). DOI: 10. ...

Researchers at University of Tsukuba have discovered a novel mechanism involved in brain development. They found that small ...

The paper, titled "Sex- and age-dependent genetics of longevity in a heterogeneous mouse population," is in the October 2022 issue of Science. Source: University of Tennessee Health Science Center ...

Scientists have engineered a hybrid mouse with a gene that predates all animal life. The team replaced a single gene in the mouse stem cells with a version from an ancient, single-celled ancestor ...

De-extinction startup Colossal Biosciences has gene-edited mice to have mammoth-like features, creating what the company calls the Colossal Woolly Mouse. The lab mice, which have been modified to ...

Scientists at The Jackson Laboratory (JAX) have developed mouse models that survive premature death and enable pre-clinical ...

Genes that modulate aging, lifespan Date: October 5, 2022 Source: University of Tennessee Health Science Center Summary: Scientists are exploring the elaborate interplay between genes, sex, growth ...

A gene-edited mouse created with two male parents has now survived to reach adulthood. This is a momentous occasion for genetics, as previous attempts to create bi-paternal mice have failed for a ...

More information: Lei Chang et al, Droplet Hi-C enables scalable, single-cell profiling of chromatin architecture in heterogeneous tissues, Nature Biotechnology (2024). DOI: 10.1038/s41587-024-02447-1 ...