Over the past fifteen years, great strides have been made to understand how heterotrimeric G proteins control their downstream targets. However, the mechanism by which heterotrimeric G proteins ...

Heterotrimeric G-proteins are components of the signal transduction pathways for the soluble and cell-contact signals that regulate normal growth and differentiation. There is now a greater ...

The effectors of GPCR activation include the heterotrimeric G-proteins Gα, Gβ and Gγ. Activated GPCRs serve as guanine-nucleotide-exchange factors (GEFs) and exchange GDP for GTP in the Gα ...

Heterotrimeric G proteins are important in G protein-coupled receptor signaling, which is important in the detection of various stimuli. Here, researchers found that the protein that regulates ...

The most elaborate heterotrimeric G-protein network known to date in the plant kingdom has just been identified. The most elaborate heterotrimeric G-protein network known to date in the plant ...

GPCRs at the cell surface are coupled to a membrane-associated heterotrimeric complex of ... Regulator of G protein signaling (RGS) proteins control signal termination by serving as GTPase ...

GPCRs are the seven membrane-spanning domains whose cytoplasmic loops and tails bind the heterotrimeric G protein complexes. Through ligand binding, guanosine diphosphate bound by an alpha subunit ...

Prostaglandin E2 (PGE2), a bioactive lipid derived from arachidonic acid, mediates a broad range of physiological processes through four G ...

Prostaglandin E2 (PGE2), a bioactive lipid derived from arachidonic acid, mediates a broad range of physiological processes through four G protein-coupled receptor (GPCR) subtypes: EP1–EP4. While the ...

The most elaborate heterotrimeric G-protein network known to date in the plant kingdom has been identified by Dr. Sona Pandey, principal investigator at the Danforth Plant Science Center.