The hexamer-octamer transition defines a new mechanism for metal ion–dependent allosteric regulation of protein function. Figure 4: The allosteric magnesium-binding site of PBGS is not present ...

Insulin protein structure is different among different species of ... The other surface is more extensive and disappears when a hexamer is formed. This is called the quaternary structure of ...

The holocomplex is a hexamer of a bipartite structure composed of a membrane-proximal ATPase domain and ... these four proteins formed a stable quaternary complex during protein purification ...

This is a view of the CA protein hexamer, which makes up the HIV capsid. This image, which reflects a perspective from inside the capsid, is a superposition of the structures reported in the new ...

Membrane proteins are key components of living cells. They constitute one-third of the ORFs of virtually all genomes, perform crucial roles, and are targeted by a huge number of drugs. When ...

DLS and SLS techniques detect protein aggregation and denaturation, ... The precision of dynamic light scattering measurements is sufficient to distinguish changes in protein quaternary structure. ...

This lack of reactivity is analogous to that of the E A and E B regions of the α3NC1 subunit. 11,25 However, disruption of the hexamer quaternary structure after treatment with guanidine or by ...

This is the proposed chemical structure of the sHM crosslink. (Top) Schematic of the alpha1alpha2alpha1 collagen IV network illustrating the interaction between the NC1 domains of triple-helical ...

Defects in type IV collagen, a collagenous protein involved in the formation of basement membranes, have been implicated in hereditary Alport's syndrome and acquired Goodpasture's syndrome.

Bacterial microcompartment shells are built out of thousands of protein subunits that fall into three basic structural motifs: ... BMC-H, which forms a hexamer, and BMC-T, which forms a trimer. These ...