The scientists loaded BI-hTFR1 viruses with luciferase genes, then added them to primary and cultured human brain endothelial cells. These cells shunt transferrin from the blood into the brain ...

Researchers have developed an engineered adeno-associated virus (AAV) vector that yields high transduction of brain vascular pericytes and smooth muscle cells.

In this report, we show that the re-introduction of the DNA flap sequence of HIV-1 in the HR vector enhances gene transfer in various primary neural cells (i.e., human neural progenitors, human ...