One candidate molecule to regulate Plasmodium rDNA transcription is the highly conserved ... by PfSir2a at temperatures normally found in the human (37 °C) and mosquito (26 °C) hosts ...

Factors that promote the transcription of rDNA increase connections ... century-old observation of connections between particular human chromosomes. In an article recently published in the ...

In this study, the researchers estimate that they identified between 18% and 47% of all human transcription factor pair motifs, greatly adding to their understanding of the regulatory code.

This makes the region an ideal place to insert a gene for human gene therapy. Collins admitted that a lot is still unknown about how R2 works and that questions remain about the biology of rDNA ...

Within the nucleolus, rDNA transcription is highly regulated ... Berkeley This makes the region an ideal place to insert a gene for human gene therapy. Collins admitted that a lot is still ...

“These Dcr1-terminated loci correspond to sites of replication stress and DNA damage, likely resulting from transcription-replication collisions,” wrote the authors. “At the rDNA ...

The researchers say the next goal will be to introduce the same stabilizing rDNA effects in human cells, which are more difficult to work with than yeast. Simply introducing Sir2 into human genes ...

Principal investigators (PIs) are required to submit an application to use rDNA, synthetic nucleic acids, biohazardous agents or unfixed human fluids and tissues prior to the initiation of the ...

Get Instant Summarized Text (Gist) Research has advanced the understanding of human gene regulation by identifying transcription factor sequences that bind to DNA, influencing gene expression. The ...