Because the nucleolus is the site of rDNA transcription, ... harbouring a human rDNA fragment spanning bases −411 to +375 relative to the transcription initiation site was linearized with EcoRI.

European Journal of Human Genetics - The sub-nucleolar localization of PHF6 defines its role in rDNA transcription and early processing events Skip to main content Thank you for visiting nature.com.

In this study, the researchers estimate that they identified between 18% and 47% of all human transcription factor pair motifs, greatly adding to their understanding of the regulatory code.

Thanks to super-resolution microscopy, scientists have now been able to unambiguously identify physical associations between human chromosomes. The findings have brought to light a new ...

Within the nucleolus, rDNA transcription is highly regulated, and the genes undergo quick repairs, ... Because some cells turn off many of the 400+ rDNA genes in the human genome, ...

Within the nucleolus, rDNA transcription is highly regulated, and the genes undergo quick repairs, since any rDNA breaks, if left to propagate, could shut down protein production. As a result, ...

Within the nucleolus, rDNA transcription is highly regulated, and the genes undergo quick repairs, ... Because some cells turn off many of the 400+ rDNA genes in the human genome, ...

The genome is a crowded, busy place, particularly along stretches containing genes required for basic survival. In these regions, transcription is nearly constant, which means that DNA’s ...