Therefore, for each gene in a cell, the ratio of unspliced mRNA to spliced mRNA can be used to directly infer instantaneous expression dynamics — that is, the ‘RNA velocity’ of each gene ...

While aggrecan gene expression did not correlate with matrix deposition in MSCs, ... our findings in MSCs show that instantaneous aggrecan expression is only tenuously connected to matrix deposition.

Investigating how mutations in tumors alter DNA’s 3D structure—and subsequently, regulatory sequences called enhancers—can offer new treatment opportunities.

Imagine that you want to know the plot of a movie, but you only have access to either the visuals or the sound. With visuals ...

Professor Hirohide Saito (Department of Life Science Frontiers at CiRA / The University of Tokyo) and Assistant Professor ...

Bioluminescent imaging is helping researchers better understand the effectiveness of tissue regeneration enhancers delivered to injured heart tissue by different adeno-associated virus vectors.

Gene expression in the human brain: cell types become more specialized, not just more numerous Date: January 2, 2025 Source: University of California - Santa Barbara ...

The duration of expression of the gene Cdx2 is tightly regulated by a newly identified DNA sequence element called an “attenuator.” ...

Through the citrullination of histones, these enzymes facilitate chromatin relaxation, enabling access for RNA polymerase II and transcriptional machinery to initiate gene expression.

Recently discovered protein turbocharges gene expression An ancient protein found in all human tissues enhances gene activation and may be involved in diseases such as cancer Date: March 10, 2022 ...

Please use one of the following formats to cite this article in your essay, paper or report: APA. Kumar Malesu, Vijay. (2024, January 12). Scientists develop noninvasive way to monitor gene ...

Second, gene expression data implicitly accounts for environmental factors, which can turn genes "up" or "down" to perform various functions. "Environmental factors might not affect DNA, ...