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Boosting or repairing the insulin production and secretion process in the special pancreatic cells, called "beta cells," where the hormone is made, would seem an obvious therapeutic strategy for ...
The finding makes possible a deeper scientific understanding of the insulin secretion process—and how it fails in insulin disorders such as type 2 diabetes.
Researchers are reporting the identification of a new biochemical pathway to control insulin secretion from islet beta cells in the pancreas, establishing a potential target for insulin control.
Hu and colleagues showed a protein controlling the PI3K/Akt pathway, a pathway targeted by more than 40 anti-tumor drugs, is absolutely required for the synthesis, processing and secretion of insulin.
A new research paper was published in Aging (Aging-US) Volume 17, Issue 5, on May 1, 2025, titled “Oxytocin modulates insulin and GLP-1 secretion in pancreatic islets.” ...
High insulin levels tied to obesity pathway Date: August 25, 2014 Source: UT Southwestern Medical Center ... Insulin blocks the secretion of glucagon, opposes glucagon action on the liver, ...
Both type 1 and type 2 diabetes possess a significant genetic component.
Researchers from Osaka Metropolitan University have identified a gene that, when activated by metabolic stress, damages pancreatic β-cells—the cells responsible for insulin production and blood sugar ...