One class of ARTs, integrase inhibitors, has become a standard HIV treatment. Research shows they work well to keep the disease in check. Here’s what you need to know. Integrase inhibitors are ...

Recipients of integrase inhibitor treatment were significantly more likely to develop IRIS according to either definition (odds ratio 3.25, 95% CI 1.83-5.80). Use of corticosteroids (23% vs 13%, p = 0 ...

Previous antiretroviral experience did not affect the risk, nor did CD4 count or viral load at the time of beginning integrase inhibitor treatment. What do these findings mean for antiretroviral ...

No writing assistance was utilized in the production of this manuscript. Dolutegravir is an HIV integrase strand transfer inhibitor (INSTI) that does not require pharmacokinetic boosting ...

Dublin, Sept. 27, 2023 (GLOBE NEWSWIRE) -- The "Integrase Inhibitors Market, By Distribution Channel, By Region, By End User, and By Geography- Size, Share, Outlook, and Opportunity Analysis ...

The HIV protein integrase (blue) can insert viral DNA (red) at different locations in the DNA of its human host (orange). But how the virus selects its insertion points has puzzled virologists for ...

Insight into the state of HIV-1 drug resistance for ARVs targeting integrase is limited in many parts of the world due to historically restricted access to integrase-targeting genotyping products and ...

The royalty levels are aligned with those in Shionogi’s existing integrase inhibitor agreements with ViiV Healthcare. Shionogi will contribute to development costs up to an annual maximum.

A panelist discusses how the new doravirine and islatravir combination offers an alternative to integrase inhibitor-based therapies, particularly useful for patients with integrase inhibitor ...

SAILING is a Phase III, randomized, double-blind, double-placebo, multicenter, parallel-group, noninferiority study in antiretroviral treatment-experienced, integrase inhibitor-naive, HIV-1 ...

Insight into the state of HIV-1 drug resistance for ARVs targeting integrase is limited in many parts of the world due to historically restricted access to integrase-targeting genotyping products and ...