One class of ARTs, integrase inhibitors, has become a standard HIV treatment. Research shows they work well to keep the disease in check. Here’s what you need to know.

Treatment with an integrase inhibitor was associated with an increased risk of heart attack or stroke during the first two years of exposure to the drug class when compared to treatment with other ...

This definition, together with the requirement for hospitalisation, resulted in a much smaller number of clinical events being classified as IRIS. The incidence of IRIS was, therefore, much lower than ...

Forty-eight weeks after the switch, virologic suppression (to fewer than 50 copies/mL) was maintained among 94.3% of those on the integrase inhibitor–based regimen, compared with 86.8% of those ...

An expert physician reflects upon the notable adverse effect of weight gain seen in HIV care with integrase inhibitors and the implications of recent study results. Moti Ramgopal, MD, FACP, FIDSA ...

A novel integrase inhibitor, S/GSK1349572, achieved undetectable HIV RNA levels with relatively few adverse events after 10 days of monotherapy in 70% of HIV-positive patients in a phase 2a study.

The HIV protein integrase (blue) can insert viral DNA (red) at different locations in the DNA of its human host (orange). But how the virus selects its insertion points has puzzled virologists for ...

During this webinar, we will focus on the state of HIV-1 evolution in light of the WHO HIV Drug Resistance Report for 2021 by discussing the surveillance efforts in South Africa and highlight the ...

A panelist discusses how the new doravirine and islatravir combination offers an alternative to integrase inhibitor-based therapies, particularly useful for patients with integrase inhibitor ...

Integrase Inhibitors Drop Virus Faster in Pregnant HIV Patients — Raltegravir, dolutegravir both appear safe and effective in late stage pregnancy by Ed Susman, Contributing Writer, MedPage ...

Vaginal gel with integrase inhibitor shows promise in monkeys Date: June 8, 2010 Source: Microbicides 2010 (International Conference on Microbicides) ...