The orderly arrangement of cells in tissues depends on complex signaling between cells. Learn how cellular junctions play important roles in cell adhesion and communication.

Janssen opted not to continue with the first two integrin targets at the end of 2021, due to "a lack of target validation in the specific disease of Janssen's interest," and has now dropped the ...

The detailed sequence of events following ECM binding to the integrin is not known, but the β-subunit cytoplasmic domain interacts directly with talin, and talin interacts with both vinculin and ...