In a significant step toward improving targeted cancer therapy, researchers from Japan have developed a novel nanocarrier ...

Adenosine deaminase 2 (ADA2) plays a critical role in immune regulation, particularly in monocyte differentiation and ...

In recent years, the regulatory role of the gut microbiota in the initiation and progression of colorectal cancer (CRC) has attracted growing attention. Among the key microbial contributors, ...

A breakthrough in cancer therapy: metal-phenolic nanocarriers deliver antibodies directly to cancer cells, improving ...

Researchers create nanomachines using metal and polyphenols, which enhance targeted intracellular delivery of antibodies for ...

Targeting intracellular checkpoints could be combined with other strategies, such as tumor sensors, immune checkpoint blockade, and synthetic gene circuits, to enhance NK cell immunotherapy.

In a significant step towards improving targeted cancer therapy, researchers from Japan have developed a novel nanocarrier ...

Targeting intracellular checkpoints could be combined with other strategies, such as tumor sensors, immune checkpoint blockade, and synthetic gene circuits, to enhance NK cell immunotherapy.

Researchers explore targeting intracellular tau aggregates for destruction, offering potential therapeutic advancements in neurodegenerative diseases like Alzheimer's.

Inhibiting promising intracellular checkpoint targets like CISH have dramatic anti-cancer potential, but have traditionally been thought to be undruggable," said Emil Lou, M.D., Ph.D., Principal ...

Halda Therapeutics Announces First Patient Dosed in Phase 1/2 Clinical Trial Evaluating HLD-0915 in Metastatic Castration-Resistant Prostate Cancer ...

Parabilis’s ERG degrader overcomes this challenge by using the company’s proprietary Helicon peptide technology, which enables intracellular targeting of “flat” protein surfaces.