Pain is good. Or finding non-opioid ways to manage it is good, if Latigo Biotherapeutics’ $150 million March fundraise is ...

Today it seems self-evident that neurons make their electrical signals by opening gates of water-filled pores (ion channels) in the plasma membrane. But it was not always so. Remarkably ...

The researchers also determined the mechanisms by which phenamil, an ion-channel blocker, inhibits the flow of sodium ions through the stator. The findings of this study could have important ...

Ion channels are integral membrane protein assemblies that modulate the flow of ions into and out of a cell or organelle, leading to generation of electrical signals. Opening (gating) of ion ...

With a sustained block of the SNS, the researchers observed loss of the day-night rhythm in sinus node pacemaking and in pacemaking ion channels. Surprisingly, the heart’s local circadian clock ...