Scientists at Fox Chase Cancer Center have identified a mutation in a common oncogene—a gene that can cause cancer—that may ...

APC is a tumor suppressor gene and is inactivated in 80% of colorectal cancers. The team found that combined inactivation of SOX9 and APC resulted in more invasive tumors than APC inactivation alone.

Colorectal cancer is the fourth most common and second deadliest cancer. How colorectal cancer develops is not well understood, but a team led by researchers at Baylor College of Medicine reports in ...

The discovery may explain why cutting edge CAR T-cell therapy has managed to revolutionized treatment for blood cancer but ...

Study identifies new gene that drives colon cancer Inflammation and tumor microenvironment also fuel and sustain it Date: October 17, 2022 Source: The Mount Sinai Hospital / Mount Sinai School of ...

Scientists from Johns Hopkins University report that a particular "key" may be fueling colon cancer, especially among younger people — and they are looking for ways to turn it off.

Millions of people in the U.S. have a genetic variant that raises their risk of cancer. Genetic testing can help people find cancer earlier and seek treatment. But many patients aren't offered it.

Through timing analysis, the study uncovered that specific genetic alterations, such as those in APC, TP53, KRAS, BRAF, ZFP36L2, TCF7L2, FBXW7, BCL9L, and SOX9, tend to occur early in the cancer ...

Interestingly, colorectal tumors with the gene p16 turned off were growing in a microenvironment that suppressed the immune response against the tumor, favoring cancer growth. These observations ...

Researchers at Mount Sinai's Tisch Cancer Institute have identified a new gene that is essential to colon cancer growth and found that inflammation in the external environment around the tumor ...

Interestingly, colorectal tumors with the gene p16 turned off were growing in a microenvironment that suppressed the immune response against the tumor, favoring cancer growth.

New York, NY (October 17, 2022) — Researchers at Mount Sinai’s Tisch Cancer Institute have identified a new gene that is essential to colon cancer growth and found that inflammation in the ...