Naturally occurring mutations within the LMNA gene, which encodes nuclear lamin, have been identified ... will improve our knowledge of nuclear envelope function, as well as the pathogenesis ...

More information: Yohei Kono et al, Roles of the lamin A-specific tail region in the localization to sites of nuclear envelope rupture, PNAS Nexus (2024). DOI: 10.1093/pnasnexus/pgae527 Provided ...

the RL/M pattern is given by autoantibodies directed against constituents of the nuclear envelope (NE), including gp210, lamin B receptor (LBR) and nucleoporin p62; the MND pattern mainly ...