Leigh Syndrome is a rare genetic disease in which mitochondria—the parts of cells that produce energy using oxygen—don't work efficiently, causing unused oxygen to build up within tissues.

The United Mitochondrial Disease Foundation states that faults in more than 75 genes can result in Leigh syndrome. For example, most people inherit the condition in an autosomal recessive pattern .

Scientists have discovered drugs which can be used to treat Leigh syndrome, a genetic form of mitochondrial disease. The findings were recently published in the journal Human Molecular Genetics ...

Their method is the first to directly fix flaws in animals’ mitochondrial DNA, which are responsible for severe and deadly ...

Leigh Syndrome and TTI-0102. Mitochondria are critical intracellular "powerplants" that provide the cell with the energy it needs to function normally; the disruption of mitochondrial function can ...

New York, USA, May 26, 2025 (GLOBE NEWSWIRE) -- Evolving Landscape of Mitochondrial Disease Market: Key Insights of Latest Published Report—Leigh Syndrome, Leber’s Hereditary Optic Neuropathy ...

Leigh Syndrome is the most common form of mitochondrial disease. The cause of this group of diseases is a malfunction of the mitochondria -- the organelles responsible for generating energy for ...

Leigh syndrome is a rare mitochondrial disease particularly affecting the organs and tissues that require most energy: the muscles and nervous system.

Mitochondria are often called the powerhouses of the cell. ... An example of a phenocopy is Leigh syndrome, which can be due to several different mutations.

Leigh Syndrome is a rare genetic disease in which mitochondria—the parts of cells that produce energy using oxygen—don't work ...

SURF1 deficiency is the most common nuclear genetic cause of Leigh syndrome. The SURF1 gene is critical for transforming nutrients into energy that can be used by our cells.