Journal of Human Genetics - Leigh syndrome caused by mitochondrial DNA G13513A mutation: frequency and clinical features in Japan Skip to main content Thank you for visiting nature.com.

Ashkenazi Jewish founder mutation has been identified for Leigh Syndrome. Leigh syndrome is a complex disorder typically caused by dysfunctional mitochondria. About Careers MedBlog Contact us ...

Leigh’s disease is a rare mitochondrial disorder caused by the disruption of the mitochondrial respiratory chain or of an enzyme which feeds substrate into this chain. It may be transmitted via ...

Researchers from the Mitochondrial Medicine Frontier Program at Children's Hospital of Philadelphia have found that developmental delays associated with Leigh syndrome, the most common pediatric ...

The United Mitochondrial Disease Foundation states that faults in more than 75 genes can result in Leigh syndrome. For example, most people inherit the condition in an autosomal recessive pattern .

Scientists have discovered drugs which can be used to treat Leigh syndrome, a genetic form of mitochondrial disease. The findings were recently published in the journal Human Molecular Genetics ...

Leigh Syndrome is a rare genetic disease in which mitochondria—the parts of cells that produce energy using oxygen—don't work efficiently, causing unused oxygen to build up within tissues.

Leigh Syndrome and TTI-0102. Mitochondria are critical intracellular "powerplants" that provide the cell with the energy it needs to function normally; the disruption of mitochondrial function can ...

Researchers from the Mitochondrial Medicine Frontier Program at Children's Hospital of Philadelphia (CHOP) have found that developmental delays associated with Leigh syndrome, the most common ...

Mitochondrial diseases are characterized by chronic, genetic and progressive medical symptoms that arise due to inherited or spontaneous mutations in mitochondrial DNA (a small, circular, double ...

Leigh syndrome is a rare mitochondrial disease particularly affecting the organs and tissues that require most energy: the muscles and nervous system.