Linkage disequilibrium (LD) mapping was used to follow up reports of linkage between reading disability (RD) and an 18 cM region of chromosome 6p21.3–22. Using a two-stage approach, we tested ...

Linkage disequilibrium testing of the candidate region by TDT. Each of the markers typed for linkage was also tested for linkage disequilibrium by the TDT using GENEHUNTER 2.0 and TDTEX programs.