Only groups which produce concentrated urine (birds and mammals) have the loop of Henle, formed from a very long intermediate portion. In mammals, the intermediate section and the loop of Henle is ...

Diuretics that exert their primary action on the thick ascending loop of Henle are most commonly used ... cardiac fibrosis that may reduce systolic function, increase cardiac stiffness, and ...

Bumetanide, a loop diuretic, inhibits sodium reabsorption in the ascending limb of the loop of Henle, as shown by marked ... Monitor electrolytes, blood, liver function. May need K+ supplementation.

Figure 3: ClC-K2 (ClCKB) is important for NaCl reabsorption in the thick ascending limb of the loop of Henle (and the distal convoluted tubule). Our knowledge of the localization, function ...