Investigators assessed the frequency of lupus flares in patients with kidney failure undergoing dialysis or with a kidney transplant.

The treatment of lupus nephritis has been studied in much more ... and reduce long-term damage (Table 4). Angiotensin-converting enzyme inhibitors and angiotensin receptor-blocking agents have ...

At univariable analysis, both anti-C1q antibodies and non-use of hydroxychloroquine predicted renal flares at baseline and 6 and 12 months. Proteinuria (24/h proteinuria and proteinuria 0.5 g/day or ...

Conventional lupus nephritis (LN) treatment based on cyclophosphamide, steroids and, recently, mycophenolatemofetil has improved the outcome of the disease over the last 50 years, although failure ...

Patients with severe lupus nephritis who have both diffuse proliferative (class IV) and membranous (class V) lesions on biopsy can be refractory to current monotherapy treatments. Bao et al.

Roche’s Gazyva is already approved in leukaemia and lymphoma – but could it work in the autoimmune kidney disease Lupus nephritis too? Gazyva (obinutuzumab) works by targeting CD-20 ...

as an option for adults at the more severe end of the lupus nephritis spectrum, in other words, those with class 3, 4, and 5 disease, according to the guidance. The drug was approved by the ...