He labeled proteins and followed them in their journey through the cell. He observed that the lysosomes described by de Duve contained fragments of the labeled proteins, and concluded that ...

Ferroptosis, a form of programmed cell death mediated by iron, has been a focus for its potential in cancer therapies. Now, researchers have discovered that lysosomal lipid peroxidation plays a ...

A closer look at gene expression in cells derived from the animal models showed that STING also increased the activity of genes associated with lysosome repair and new lysosome generation.

For neurodegenerative diseases such as Alzheimer's and Parkinson's, treatment options are scant. New research by Stanford ...

In a paper published in Nature Communications, researchers from Kyushu University, using cultured cells and mice, found that the lipid peroxidation of the lysosomes—the organelle responsible for ...

Trafficking occurs in both directions; the forward direction takes vesicles from the site of synthesis to the Golgi apparatus and next to a cell's lysosomes or plasma membrane. Vesicles that have ...

Scientists have been searching for treatments for neurodegenerative disorders like& Alzheimer's and Parkinson's for many years... | Genetics And Genomics ...

Research had already established one way that cells repair leaky lysosomes. Previously, a collection of proteins known as the ESCRT machinery was found to patch up holes in the organelles’ membranes.

get out of cells via lysosomes, organelles responsible for taking out cellular garbage, rather than using the biosynthetic secretory pathway used by most other enveloped viruses. “There hasn't been a ...

In a paper published in Nature Communications, researchers from Kyushu University, using cultured cells and mice, found that the lipid peroxidation of the lysosomes—the organelle responsible for ...