DNA methylation is one of several epigenetic mechanisms ... Likewise, demethylated DNA does not attract deacetylating enzymes to the histones, allowing them to remain acetylated and more mobile ...
A study conducted by a research team from Kumamoto University has shed light on the critical role of a tRNA methylation enzyme, TRMT10A, in supporting brain function. The findings reveal how the ...
Northwestern Medicine investigators have discovered previously unknown metabolic changes that may contribute to the ...
Although DNA methylation and histone modification are carried out by different chemical reactions and require different sets of enzymes, there seems to be a biological relationship between the two ...
Concurrent analysis of whole-genome DNA methylation and single-cell RNA sequencing data from COVID-19 patients and controls reveals gene regulatory alterations in airway epithelial and immune cells.
With RRBS, scientists enrich for GC-rich parts of the genome by digesting the DNA with an enzyme that generates fragments with CpG dinucleotides at both ends, independent of methylation status. This ...
Liver TET1 was found to promote metabolic dysfunction-associated steatotic liver disease (MASLD) by regulating CD36 ...
This rather complex six-protein system is interesting because it combines classical DNA methylation with new antiviral mechanisms. In this study, we tried to find out how BREX distinguishes ...
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