4 Microglial cells are critical for the maintenance of CNS homeostasis, immune responses and neural functions. They are highly dynamic, continuously moving throughout the CNS and monitoring their ...

A new study investigates how APOE isoforms differentially affect human microglia function in Alzheimer's disease ...

A recent study published in Nature Communications provides insight into how APOE isoforms alter human microglia activity in ...

A new study, published today in Nature Communications, offers clues into how APOE isoforms differentially affect human ...

Many of these treatment options fail to address the toxic effects of the myelin debris that accumulate in the nervous system, which can kill cells. Microglia play important roles in healthy brain ...

In some of the stem cells they then used CRISPR gene editing ... the gene expression measurements and the evidence from microglia function experiments, the researchers were able to formulate ...

As other cells age, they can complicate microglial function, making them less effective. But the underlying mechanism of how microglial cells age and how their aging directly affects the brain is ...

However, cultured microglia generated from iPS cells bear little resemblance to their in-vivo ... In addition, her group is adding proteomic data, which will offer more clues about the function of ...

Microglia are the brain's immune cells known to play a vital role in maintaining neural function and responding to potential threats. However, when the brain is subjected to hyperosmotic stress ...