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The Buccal Micronucleus Cytome (BMCyt) assay is a minimally invasive method for studying DNA damage, ... Preparation and transfer of cells onto the microscope slides using a cytocentrifuge. i.
All of the DNA in the micronucleus is copied thousands of times over, and shunted into the macronucleus. In the process, it is broken up at tens of thousands of places, rearranged, and pruned.
Specifically, the authors use the Buccal Micronucleus Cytome (BMCyt) assay, which they describe as “a minimally invasive method [that] has shown advantages as it is used not only for detecting ...
Study: Genetic determinants of micronucleus formation in vivo.Image Credit: Dimarion/Shutterstock.com. Background. Genomic instability and extracellular MN accumulation are hallmarks of various ...