Researchers at Karolinska Institutet and Uppsala University have developed a powerful new technique to better understand how ...

Researchers at Karolinska Institutet and Uppsala University have developed a powerful new technique to better understand how ...

Such gene signatures, however ... Most commercially available technologies for global miRNA expression profiling are based on DNA microarrays, in which the probes are spotted onto a glass surface.

Many diseases are caused by a missing or defective copy of a single gene. For decades, scientists have been working on gene ...

miRNA Discovery Phase PBMC miRNA expression was assessed by small RNA sequencing, using pools of equal amounts (1 µg) of RNA from PDAC patients (n = 20), those with benign pancreatic disease ...

Figure 1: Using microRNA target sites to target transgene and viral expression. Gene and cell therapy. We first showed that endogenous miRNA regulation can be used to improve vector control when ...

MIT engineers have designed a new method to improve the precision of gene therapy treatments by using gene circuits that ...

This valuable study provides insights into a key question in comparative neuroanatomy and development. The authors provide evidence of the role for a particular micro-RNA in regulating the development ...

miRNAs are important negative gene regulators that have critical roles ... The evaluated study examined the miRNA profiles in peripheral blood mononuclear cells from PDAC patients.