Mitochondria are crucial organelles for cellular homeostasis, regulating processes such as ATP production, reactive oxygen ...

“High calcium levels in the mitochondria cause oxidative stress, and the death of neurons via apoptosis,” says lead author of the paper, Maria Calvo-Rodriguez.

Stress pushes cells to die when gatekeeper of calcium use in mitochondria is dysfunctional Search is now on for agent that can inhibit the calcium overload, cell death that causes damage during ...

Calcium in the mitochondria -- the energy factory of cells -- may be one of the keys to understanding and treating Alzheimer's disease and dementia. Researchers have now identified how an ...

Mitochondrial Targeting: The introduction of a mitochondrial matrix targeting sequence results in mt-TurCaMPb, which is tailored for the specific detection of calcium elevations within mitochondria.

Mitochondria are often called the powerhouses of the cell. We explain how they got this title, and outline other important roles that they carry out. ... Because calcium is so critical, ...

The new research, published in the journal Science Signaling, is the first to show that mitochondrial ultrastructure is regulated by the calcium-binding protein MICU1. MICU1 is necessary for ...

Led by Prof. Dr. Markus Schwarzländer, an inter-university team recently discovered how calcium ions find their way into the mitochondria of plant cells. The vital signalling substance is ...

Inhibiting the transfer of calcium ions into the cell's powerhouse is specifically toxic to cancer cells, according to an article published this week in Cell Reports by researchers from the ...