Hyperpolarization-activated cation channels of the HCN gene family1,2,3,4,5,6 contribute to spontaneous rhythmic activity in both heart7 and brain5,6,8. All four family members contain both a core ...

Molecular Psychiatry - HCN-channel dendritic targeting requires bipartite interaction with TRIP8b and regulates antidepressant-like behavioral effects. ... schematized by a red shape.