A new concept of kinetic modules in biochemical networks could revolutionize the understanding of how these networks function ...

Through further studies, Kozicka's team has identified more than 40 different molecular glue degraders. The scientists have also mapped out the structures of molecular complexes induced by many of ...

Roche's Genentech is sticking with Orionis Biosciences, handing over $105 million upfront as part of its second deal with the ...

Blueprint Medicines is revising a pact with VantAI again, this time adding a focus for historically “undruggable” targets and ...

The work entailed designing, synthesizing and screening the molecular glue library, structure-guided medicinal chemistry optimization, and testing in patient-derived cancer cells. It was only ...

The researchers showed that the molecule UM171 works as a glue that can trigger the breakdown ... the team discovered that cancer mutations alter protein structure and function, mirroring the ...

The team then added a molecular “glue” to the ink that, when laser activated, formed stable bonds between the nanocrystals, resulting in robust 3D structures. Because of the versatility of the ...