The report assesses the active GABA Transaminase Inhibitor pipeline products by developmental stage, product type, molecule type, and administration route. Reasons to Buy. Establish a comprehensive ...

In a groundbreaking review paper published in Nature Reviews Neuroscience, scientists have shed new light on the role of GABA, a key signaling molecule in the brain. Researchers from the Center ...

Analysis of immune cells shows that, unexpectedly, B cells secrete GABA, a molecule best known as a neurotransmitter. B-cell-derived GABA can modulate immune responses against tumours, ...

Scientists have shed new light on the role of GABA, a key signaling molecule in the brain. Researchers have delved into how GABA's levels in the brain are regulated and its broader impacts on ...

GABA transaminase catalyzes GABA turnover to succinic semialdehyde, which in turn is turned over into succinic acid by succinic semialdehyde dehydrogenase, recycling the carbon backbone to the ...

GABA production in the liver is governed by an enzyme called GABA transaminase. The researchers blocked production of this enzyme in type 2 diabetes animal models to test whether the mechanism ...

A new study in a mutant fruit fly called sleepless (sss) confirmed that the enzyme GABA transaminase, which is the target of some epilepsy drugs, contributes to sleep loss. The findings, published ...

Upon blocking the genes required for GABA synthesis, transport, and maturation, the researchers observed decreased induction of metamorphosis, confirming they had found the right regulatory molecule.

Adding those molecules -- a GABA-like molecule and another, called a positive allosteric modulator or PAM, that fine-tunes GABAB function -- stabilized GABAB receptor in its active state.

These bacteria consume GABA, a molecule crucial for calming the brain, and the fact that they gobble it up could help explain why the gut microbiome seems to affect mood.

Using Cryo-EM, a powerful microscopy technique, researchers at IISc and collaborators have decoded the molecular architecture of a transporter protein controlling the movement of a key ...

GABA, or gamma aminobutyric acid, is one of the main neurotransmitters in mammals. It is usually thought of as an inhibitory molecule because it blocks certain signals in the brain, decreasing ...