Scientists identify marker for myeloid-derived suppressor cells. ScienceDaily. Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2016 / 08 / 160805154941.htm. The Wistar Institute.

Clu + HSCs showed an increased propensity towards differentiating into platelets or myeloid cells. In the bone marrow, Clu + HSCs preferred self-renewal over differentiating into other cell types.

Through single-cell RNA-sequence analysis comparing young mice (8–10 weeks old) with aged mice (18–20 months old), the researchers identified Clusterin (Clu), a molecular chaperone, as a novel ...

Cell line sensitivity and additional patient data. A IC50s for VEN of 19 AML cell lines classified as primitive (Prim-AML, n = 11) or monocytic (Mono-AML, n = 8) treated ex vivo with 1.5 µM of 5 ...

Please use one of the following formats to cite this article in your essay, paper or report: APA. Sartorius. (2023, June 09). Screening memory T cell frequency using an optimized, multiplex flow ...

Allogenic hematopoietic stem-cell transplant (HCT) is a curative therapy for acute myeloid leukemia (AML) and myelodysplastic ... Kayser S, Levis MJ: Clinical implications of molecular markers in ...

A monoclonal antibody (mAb) that targets myeloid blast cells including the CSC without targeting the hematopoietic stem cell (HSC: CD34+90+) may be of value. CSC phenotype of CML-BC (CD34+38 ... CSC17 ...

Clusterin identified as key marker for aging in blood stem cells. 2w. ... However, with age, HSCs become biased toward differentiating into myeloid cells and platelets rather than lymphocytes.