The first article in Cell, "Development of Clinically Viable Non-Muscle Myosin II Small Molecule Inhibitors," details the optimization and development of a new pharmacological cla ...

After five years of work, a team from National Biosciences Laboratory (LNBio), in the city of Campinas, has defined the three-dimensional structure of what is called the functional, or active, region ...

At the molecular level, muscle contraction is defined by myosin molecules pulling actin filaments. New electron cryomicroscopy images with unprecedented resolution taken by researchers at Osaka ...

Study reveals molecular mechanisms behind hibernation in mammals Date: February 20, 2024 Source: eLife Summary: Researchers have characterized changes in the structure of motor proteins, called ...

How deadly parasites 'glide' into human cells Date: October 13, 2020 Source: European Molecular Biology Laboratory Summary: A group of scientists provide insights into the molecular structure of ...

Study reveals molecular mechanisms behind hibernation in mammals Researchers have characterised changes in the structure of motor proteins, called myosins, and energy consumption that occur during ...

They assessed whether hibernation affects the structure of two myosin proteins from the Thirteen-lined ground squirrel: Myh7 and Myh2. Although they did not observe any hibernation-related changes in ...

Physicists from the Universities of Bayreuth and Grenoble have discovered a new mechanism of cell mobility. Their findings challenge the classical dogma that the molecular motor myosin is ...

Researchers have shed light on the molecular mechanisms underlying hibernation, publishing their findings today as a Reviewed Preprint in eLife. Their research, in small and large hibernating mammals, ...