JUV-161 is an investigational therapeutic for the treatment of Myotonic Dystrophy Type 1 (DM1), a rare, multi-systemic, autosomal dominant inherited disease and the most common form of adult ...

The type of myotonic dystrophy that begins at birth is more serious. Other forms get worse very slowly, and can take 50 or 60 years to progress. Limb-Girdle Muscular Dystrophy ...

Towards a treatment for myotonic dystrophy: First 3D model with patient cells. Myotonic dystrophy is a hereditary degenerative neuromuscular disease that occurs mainly in adults, affecting about ...

JUV-161 is a first-in-class muscle regenerating biologic that will address myopathies starting with Myotonic Dystrophy Type 1 JUV-161 was discovered using Juvena’s proprietary JuvNET platform ...

DelveInsight’s 'Myotonic Dystrophy Pipeline Insight – 2023' report provides comprehensive global coverage of available, marketed, and pipeline myotonic dystrophy therapies in various stages of ...

More information: Preeti Kumari et al, Analysis of human urinary extracellular vesicles reveals disordered renal metabolism ...

In myotonic dystrophy, like the other types of MD, faulty DNA is to blame for the abnormalities that occur. Weakness. Myotonic dystrophy occurs because of a large expansion of DNA code, which most ...

Correction of Clcn1 alternative splicing reverses muscle fiber type transition in mice with myotonic dystrophy. Nature Communications , 2023; 14 (1) DOI: 10.1038/s41467-023-37619-1 Cite This Page : ...

Myotonic dystrophy, a slowly progressive, hereditary disease, is the most common form of muscular dystrophy, heart block being the most clinically significant type of cardiac involvement more ...

A recent discovery of a molecular connection between autism and myotonic dystrophy, a type of neuromuscular disease, may provide a breakthrough on how clinicians approach autism spectrum disorder.