Patients and Methods: Sixty patients with end-stage renal failure were randomised to receive a 4-hour intravenous infusion of N-acetylcysteine or placebo during a 4-hour haemodialysis session.

Objective: To investigate the efficacy and tolerability of high-dose N-acetylcysteine (NAC) in the treatment of patients with exacerbations of chronic obstructive pulmonary disease (COPD).

Acetadote, an intravenous formulation of N-acetylcysteine ... combines the first two standard doses into a single, slower infusion, simplifying administration and improving patient outcomes ...