Each human kidney has about 1 to 2 million filtering units called nephrons that help purify our blood and remove waste ...

In the collecting ducts, antibiotics can cause a diverse range ... Integrated with the physiology of each successive nephron segment, we discuss the receptors, transporters, channels or pores ...

Upon binding of desmopressin to V2 receptors in the basolateral membrane of the cells of the distal tubule and collecting ducts of the nephron, adenylyl cyclase is stimulated. The resulting ...

Vasopressin (a.k.a. ADH or antidiuretic hormone) helps to regulate water retention by absorbing water in the collecting ducts of the nephron. Blocking this receptor will allow water to be excreted ...

However, a persistent limitation has been that these organoids lack a collecting duct system, which is required to carry fluid out of the nephron. This has been a fundamental barrier to producing ...